:root {
  --panel: #ffffff; --ink: #0f172a; --muted: #64748b;
  --line: #e2e8f0; --accent: #1d4ed8; --accent-soft: #eff6ff;
  --macro: #7c3aed; --macro-soft: #f5f3ff; --onco: #0e7490; --onco-soft: #ecfeff;
}
* { box-sizing: border-box; }
body { margin: 0; font-family: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, Helvetica, Arial, sans-serif; color: var(--ink); background: #f8fafc; }
.wrap { max-width: 1200px; margin: 0 auto; padding: 0 20px; }
.topbar { background: linear-gradient(135deg, #0f172a, #1e3a8a); color: #fff; padding: 22px 0 22px; }
.brand { display: flex; align-items: center; gap: 14px; margin-bottom: 16px; }
.brand-logo-el { flex: 0 0 auto; }
.brand-text h1 { margin: 0 0 3px; font-size: 24px; }
.subtitle { margin: 0; color: #cbd5e1; font-size: 13.5px; }

/* Top row: stats + search side by side */
.hero-row { display: flex; gap: 16px; align-items: stretch; flex-wrap: wrap; }
.stats { display: flex; gap: 12px; flex-wrap: wrap; flex: 1 1 auto; }
.stat { background: rgba(255,255,255,0.1); border: 1px solid rgba(255,255,255,0.15); border-radius: 10px; padding: 9px 14px; min-width: 92px; }
.stat .num { font-size: 21px; font-weight: 700; }
.stat .lbl { font-size: 11px; color: #cbd5e1; text-transform: uppercase; letter-spacing: .04em; }
.search-wrap { display: flex; align-items: center; flex: 1 1 260px; min-width: 240px; }
.search-wrap input { width: 100%; padding: 11px 14px; border: 1px solid rgba(255,255,255,0.25); border-radius: 10px; font-size: 14px; background: #fff; color: var(--ink); }

/* Controls: all dropdowns in a single row */
.controls { display: flex; gap: 10px; flex-wrap: nowrap; overflow-x: auto; margin: 20px 0 10px; padding-bottom: 4px; }
.controls select, .controls button { padding: 9px 12px; border: 1px solid var(--line); border-radius: 8px; font-size: 13.5px; background: #fff; flex: 1 1 0; min-width: 132px; white-space: nowrap; }
.controls button { cursor: pointer; background: var(--accent); color: #fff; border-color: var(--accent); flex: 0 0 auto; min-width: 84px; }
.controls button:hover { background: #1e40af; }

.result-count { color: var(--muted); font-size: 13px; margin: 6px 2px 12px; }
.table-wrap { overflow-x: auto; background: var(--panel); border: 1px solid var(--line); border-radius: 12px; }
table { width: 100%; border-collapse: collapse; font-size: 13.5px; }
thead th { text-align: left; background: #f1f5f9; color: #334155; font-weight: 600; padding: 11px 12px; border-bottom: 1px solid var(--line); white-space: nowrap; position: sticky; top: 0; }
tbody td { padding: 11px 12px; border-bottom: 1px solid var(--line); vertical-align: top; }
tbody tr { cursor: pointer; }
tbody tr:hover { background: var(--accent-soft); }
.year-pill { font-weight: 700; }
.partners { font-weight: 600; }
td strong { color: #0b3ea8; }
.tag { display: inline-block; font-size: 11px; padding: 2px 8px; border-radius: 999px; margin-right: 4px; }
.tag.onco { background: var(--onco-soft); color: var(--onco); }
.tag.macro { background: var(--macro-soft); color: var(--macro); }
.modal { position: fixed; inset: 0; background: rgba(15,23,42,0.55); display: flex; align-items: center; justify-content: center; padding: 20px; z-index: 50; }
.modal.hidden { display: none; }
.modal-card { background: #fff; border-radius: 14px; max-width: 720px; width: 100%; max-height: 86vh; overflow-y: auto; padding: 26px 28px; position: relative; }
.modal-close { position: absolute; top: 12px; right: 14px; border: none; background: none; font-size: 28px; line-height: 1; cursor: pointer; color: var(--muted); }
.modal-card h2 { margin: 0 28px 4px 0; font-size: 20px; }
.modal-card .meta-row { display: flex; flex-wrap: wrap; gap: 8px; margin: 10px 0 18px; }
.dl { display: grid; grid-template-columns: 160px 1fr; gap: 8px 16px; font-size: 14px; }
.dl dt { color: var(--muted); font-weight: 600; }
.dl dd { margin: 0; }
.dl dd strong { color: #0b3ea8; }
.dl a { color: var(--accent); }
.footer { color: var(--muted); font-size: 12px; padding: 24px 20px 40px; }
@media (max-width: 640px) { .dl { grid-template-columns: 1fr; gap: 2px 0; } .dl dd { margin-bottom: 8px; } }